>At ASH, Isis scientists will present research updates on two clotting factors, Factor XI and Factor VII.<
There are several companies pursuing the FVIIa market; this is not surprising because NVO’s NovoSeven is a big-selling drug that goes off-patent in the US and EU in the next three years.
Good luck to ISIS competing against these players, some of whom are behemoths!
(In addition, LFB, the French plasma-products company, is partnered with GTCB to develop FVIIa transgenicially, but I question the seriousness of the companies’ commitment to the program.)
Unlike FVIIa, Factor XI is at best a niche market.