There is just no way I can measure the impact of the resignation of a head of R&D, when I used to run such a business, I could always replace such with ten better candidates (but rarely did, because I always prefer a known entity, even with "blemishes" on a supposedly "great new guy" which I really know nothing about). A new head of R&D is surely not going to be critical to the existing pipe line. My, quite natural after a merger of that kind. guess is, there were two such guys (one for IDEC and one for BGEN) and one of the two had to go