Prodarsan............
As a former physician member of the American Academy of Anti-Aging Medicine (A4M) I will not be rushing over to my broker to buy Pharming. Aging is a complex process involving (1)DNA (particularly in the mesenchymal tissues, ie fat, muscle, blood vessels, bone...the suporting structures.) (2) Endrocrine hormone systems particularly sex hormones which may be controlled by a poorly understood mechanism frequently referred to as a biological clock. (3) external physical injury such as radiation which produces free radicals which injure DNA, RNA and cell membranes. Plus emotional,toxilogical and hereitary factors. We think normal is 98.6F, but acually basal tempertures vary from person to person and small differences over time probably play a big role in the rate people age.
IMHO the most interesting aspect of aging involves the terminal portions of the mesenchymal DNA, these ends are called telemeres. During the course of normal cell division these telemers become shorter. After a predetermined number of divisions the telemeres reach a critical length and further cell division is not possible. This results in progressive loss of these cells during aging. Geron has long studied telemeres and their control as cancer cells contain telemerases that rebuild the DNA ends and confer an "immortality".
Reading between the lines and taking into account the progeric disease type the company selected it sounds like Prodarsan must be some free radical trap (it cuts down on DNA injury),,think Vitamin C....The fact it is a small molecule and can be given PO would be consistant with that....This is a field full of smooth operators...
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