Replies to post #3744 on Repros Therapeutics Inc (RPRX)

[Nerf]

y3max wants to know about Japanese pharma!!!!!!

[ethan77]

Thanks Doc

[Bio_pete]

Thanks for the update. Thats the best way to respond to the FUD.

Hit em straight..

Bio_pete

[corpstrat]

Thanks from me, too. Sounds good to the layperson. Wonder if Dewophile, Clark or io have comments on any of those responses.

Nice to have confirmation that there will be more efficacy data out in next 30 days and that the 4 P III trials are getting under way in this timeframe. Looks like a possible month's slippage on those (?), but that's to be expected.

Repros's is an amazingly productive team. Astonishingly under-appreciated.

[exwannabe]

Sounds just like Tony Snow interviewing Bush.

How about some real questions?

Why 15 patients in the palceboe arms of the 4 trials, especially when you know many will drop out?

Why no SPA?

The FDA does not like companies to use higher dosages than have been shown effective. For anemmia, why is the 15mg dose not in the P3?

What are the endpoints? In particular the company states the trials are 2.5X bigger than the P2s. So, this implies a composite endpoint of both arms treatment arms, or a P reduction. If composite, isn't that a danger in the fibr. trial? If a P reduction, what?


I know all these issues were beaten to death, so no need to ask. Just present the softballs.

[io_io]

Thanks for sharing Doc.....EOM