>Any idea about how easy it would be to get a protein into the lymphatic system intranasally? (NSTK)<
I cant’ tell if you’re joking or serious about NSTK.
My opinion is that NSTK’s method of delivering peptides and proteins intranasally—what the company calls its tight junction technology—does not work well enough to form the basis of a commercial product. MRK, PG, and NVO evidently agree: each of them dumped a collaboration with NSTK for intranasal delivery.