Replies to post #59943 on Biotech Values

[DewDiligence]

Re: HIV quiz

>Most viral replication occurs within cells, of various types, and the drugs don't get inside all the appropriate cells in a timely fashion before replication proceeds to the point where new viruses are released from the cells and dumped into the blood or transferred to others cells.<

That’s essentially the answer.

The half-life of an HIV virion is about one day. Hence, even if a drug is able to stop 100% of HIV replication, about 1/128 of the virions are still around after seven days. 1/128 is roughly -2 logs (base 10).