Tony nothing is stronger than a clinicians own experience in determining how they do things currently and likely in the future. Rightly or wrongly that is just the way it is. Ask any drug rep. If they get a surgeon to try a new suture device and the suture doesn't hold you can be damn sure most won't use it again despite of any paper you can wave in front of their nose highlighting the improved tensile strength of what you are trying to sell them. FYI Those papers don't impress me one bit and if the price of recombinant thrombin was $200/vial I wouldn't use it either.
It the hospital formulary changes to recombinant thrombin surgeons likely won't notice and likely won't care. Also if they then switched back the same surgeons likely won't notice or care. They would notice and likely care if they had to wait a half an hour while the thrombin was being thawed.
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