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DewDiligence

12/01/07 4:25 PM

#5792 RE: DewDiligence #5791

The description of the US Atryn trial may be found at:

http://clinicaltrials.gov/ct2/show/NCT00110513

This web page was last updated in Aug, which is the reason it shows enrollment still being open.

Compared to the older description of the trial in #msg-6632420, the only change of consequence is that patients with two hereditary deficiencies previously excluded (Factor V Leiden and prothrombin gene mutation) were allowed in. This change was made in 2006 to facilitate enrollment.