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Replies to #54348 on Biotech Values
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ThomasS

11/05/07 11:46 PM

#54349 RE: justrpaul #54348

"This finding demonstrates a correlation"
I would note that:
1. Others have attempted to show the same
2. "demonstrating a correlation" does not form an axiom.

I can flip a penny 5 times, get heads 5 times, and demonstrate a correlation.
If I flip that same penny 5000 times, I can form an axiom, albeit probably different from the original correlation!
(I'll wait for the 5000th flip before buying a "corporate" correlation)


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ThomasS

11/06/07 1:49 AM

#54351 RE: justrpaul #54348

VRTX: You're correct; it would be a more logical World!
Not to prolong this, but it is an important point... why is RVR important?
1. If a patient doesn't have RVR at 4 weeks, should they just discontinue?
2. If they have RVR, does that mean they will be cured?

Regardless, the only true indicator at 4 weeks is VR; if a patient has little or no VR at week 4, that is an indication that treatment is fruitless and not worth the 48 weeks.

"91% SVR 24 or SVR 12" is a bit misleading, wouldn't you agree?