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jessellivermore

10/31/07 8:38 AM

#5384 RE: ThomasS #5383

DIC's no slam dunk..............

IMHO DIC's lookin pretty good. AT3 in, Heparin out.

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floblu14

10/31/07 9:02 AM

#5385 RE: ThomasS #5383

>DIC is no slam-dunk.<

I repeat - err - DEW repeats -
>With a firm scientific grounding from the new preclinical data and an enhanced understanding of the ramifications of Kybersept, it would seem that GTC’s DIC program has a good chance to bear fruit.<

http://investorshub.advfn.com/boards/read_msg.asp?message_id=20150779

P.S. A toast to ATRYN, goatees. Drink up or be infused :-)
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DewDiligence

11/01/07 11:29 AM

#5414 RE: ThomasS #5383

CC and partnership musings:

Tough day for the broad market, but GTC seems to have its ducks in a row.

As Thomas S (an astute observer) noted in #msg-24150380, the economics of a US Atryn partnership will of necessity be heavily back-end loaded because the indication of greatest economic consequence (DIC) is still early in phase-2.

It would seem that, by including the modest up-front payment from a US ATryn partnership in the cash-burn guidance for 4Q07, GTC is signaling that the partnership discussions are at an advanced stage.

It’s disappointing that Leo’s phase-2 DIC trial is taking longer than expected to enroll. I hold out some hope that a US partner with deep pockets might want to augment Leo’s DIC trial (which includes no clinical sites in the US) with a US-based DIC trial. If I were representing GTC’s US partner, I’m pretty sure that I would consider such an action to be a productive use of my company’s funds.