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DewDiligence

10/15/07 3:32 PM

#2061 RE: go seek #2047

The 10/5/07 Tyzeka scripts reached an all-time
high on all measures: NRx, TRx, NRx%, and
TRx%. This is not proof of anything but it does
suggest that the overall marketing push has not
been cut on account of NVS’ taking over 100%
of the effort. (10/5/07 numbers c/o rkrw.)

Tyzeka US Scripts

[NRx=number of new prescriptions; TRx=number
of total prescriptions (new+renewal). For recently
launched drugs, the trend in NRx is an indicator of
what can be expected for TRx with a modest time lag.
NRx% and TRx% are calculated as NRx and TRx
divided by the number of new and total prescriptions,
respectively, for all drugs in the HBV category.

Note that a prescription is counted as new whenever
it is newly written, even if is for a drug the patient is
already taking.]
Date  NRx TRx NRx% TRx% 
Oct05 139 314 5.9% 4.0%
Sep28 116 299 4.9% 3.7%
Sep21 87 252 3.8% 3.3%
Sep14 100 277 4.3% 3.6%
Sep07 82 242 3.7% 3.1%
Aug31 99 318 4.1% 4.0%
Aug24 101 280 4.8% 3.6%
Aug17 101 254 4.5% 3.3%
Aug10 125 270 5.4% 3.5%
Aug03 123 265 5.3% 3.4%
Jul27 120 268 5.3% 3.5%
Jul20 102 225 4.7% 3.0%
Jul13 115 286 5.0% 3.7%
Jun29 86 214 3.8% 2.8%
Jun22 78 197 3.6% 2.7%
Jun15 91 212 4.0% 2.8%
Jun08 80 191 3.5% 2.5%
Jun01 65 167 3.4% 2.5%
May25 79 169 3.6% 2.3%
May18 80 152 3.7% 2.2%
May11 93 191 4.4% 2.6%
May04 92 188 4.1% 2.5%
Apr27 80 161 3.6% 2.2%
Apr20 76 146 3.6% 2.1%
Apr13 61 135 2.9% 1.9%
Apr06 82 137 3.9% 1.9%
Mar30 87 142 3.9% 2.0%
Mar23 55 90 2.7% 1.3%
Mar16 54 103 2.4% 1.4%