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keitern

09/12/07 9:05 AM

#1829 RE: DewDiligence #1827

How is one to interpret the data given HBV's accelerated incidence along with theoretical increased diagnosis and in light of the 2005 (Baraclude) vs. 2007 (Tyzeka) total scripts? It would seem that total scripts would be greater but Baraclude is entrenched.
Is it possible to see a dent in Baraclude sales since Tyzeka has become available? I mean, is Tyzeka a problem for Baraclude or are their sales increasing at a consistent rate irrespective of Tyzeka. Thanks
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09/19/07 7:01 PM

#1882 RE: DewDiligence #1827

Tyzeka vs Baraclude US Scripts (Rolling and Raw)

[NRx=number of new prescriptions; TRx=number
of total prescriptions (new+renewal). For recently
launched drugs, the trend in NRx is an indictor of
what can be expected for TRx with a modest time lag.
Note that a prescription is counted as new whenever
it is newly written, even if is for a drug the patient is
already taking.

Caution: these numbers should not be taken too
literally inasmuch as the “comparable dates” may not
really be comparable. Still, I think it’s a worthwhile
presentation to get a general feel for the sales ramps.]



Tyzeka vs Baraclude Rolling US Scripts
by Comparable Calendar Date
(2007 vs 2005)
Four-Week Rolling Average
          Tyzeka   Baraclude    
NRx TRx NRx TRx
09/07/07 96 274 140 311 09/09/05
08/31/07 107 281 142 306 09/02/05
08/24/07 113 267 131 279 08/26/05
08/17/07 118 264 133 267 08/19/05
08/10/07 118 257 139 267 08/12/05
08/03/07 115 261 133 250 08/05/05


Tyzeka vs Baraclude Raw US Scripts
by Comparable Calendar Date (2007 vs 2005)
          Tyzeka   Baraclude 
NRx TRx NRx TRx
09/07/07 82 242 140 335 09/09/05
08/31/07 99 318 177 379 09/02/05
08/24/07 101 280 119 274 08/26/05
08/17/07 101 254 122 254 08/19/05
08/10/07 125 270 149 317 08/12/05
08/03/07 123 265 132 269 08/05/05
07/27/07 120 268 131 229 07/29/05
07/20/07 102 225 144 252 07/22/05
07/13/07 115 286 125 250 07/15/05