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DewDiligence

09/09/07 6:46 PM

#1784 RE: rkrw #1783

Restructuring the profit share into a royalty arrangement would help a lot, IMO. I think we’ve talked about this before. I can imagine this raising the share price by $1 or more if the royalty terms are disclosed and the cash-burn guidance is greatly reduced.

The 20% figure you got on development costs may be a blended figure from the phase-2/3/3b studies and the phase-4 studies. I’ve been sloppily calling all ongoing Tyzeka studies post-marketing, but some of them are actually registrational, such as the one in decompensated liver disease.
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DewDiligence

09/11/07 2:23 PM

#1793 RE: rkrw #1783

Ron Renaud, in reply to a question about the relationship with NVS, said: “At this point, no change.”

Hmm... if no change were being contemplated, why would he add the at this point disclaimer?