You brought up the comparison to CHO cells (not me) when you said the following:
The same issues are in play for purification of proteins or antibodies from CHO cells (Chinese Hamster ovary). It may be worse since they must purify from lower yields in the initial stages. To grow tissue culture cells, the media also has additives such as calf serum, antibiotics, hormones.
Now you're trying to change the argument on the fly.