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DewDiligence

08/12/07 3:49 PM

#4565 RE: 10nisman #4564

>What Companies do you think Cox is talking to with respect to a potential partnership in the US for Atryn?<

The most logical US ATryn partners (IMO) are NVO and WYE. These companies already have a salesforce for one or more large-selling plasma-protein drugs.

GTC recently hired a business-development executive, Ashley Lawton, PhD (#msg-18432652). Dr. Lawton (rather than Dr. Cox) is probably the one leading partnership discussions.

>Assuming Atryn gets approval in the US wouldn't it make the most economic sense for a potential partner to just purchase all of GTCB ($2-4/pps) vs. some type of upfront money ($20-50 million) and profit sharing?<

I doubt that GTC’s BoD would seriously consider $2/share. If an offer came in at $4/share, the BoD would presumably put the offer up for a shareholder vote.

Even if a buyout offer were turned down, it would put a floor under the share price.

>I'm a little surprised with the share price lagging that no one has thrown out a $2-4 takeover offer.<

Stay tuned.