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DewDiligence

07/25/07 5:18 PM

#4322 RE: aslan2772 #4319

Actually, Aslan, point #3 is not valid as noted in the bottommost paragraph of #msg-21512739:

>>
…glycosylation variants are rarely a cause of immunogenicity. I guess you haven’t followed MAXY, whose raison d’etre is producing such variants deliberately. Immunogenicity is much more likely to be caused of impurities in the manufacturing process, and I addressed this issue from GTC’s perspective in #msg-21459812.

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Regards, Dew