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aslan2772

06/29/07 4:04 AM

#1315 RE: DewDiligence #1309

I got the distinct impression that MRK plans to run multiple versions of I-vation with different drugs.
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aslan2772

06/29/07 4:40 AM

#1323 RE: DewDiligence #1309

"two possibilities: 1) MRK thinks I-vation TA has commercial potential in its own right; or 2) the TA program will remain active only until another embodiment of I-vation is ready to be tested in humans. I lean toward #2."

TA might work well for DME on I-vation (recall the debate about potential benefits of keeping the dose in the low therapeutic range), plus it might be used off label to reduce the frequency of Lucentis injections. I would not discount these possibilities.