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Replies to #47915 on Biotech Values
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poorgradstudent

06/02/07 6:29 PM

#47916 RE: caravon #47915

you're confusing medians with overall risk / hazard ratios. eom.
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mouton29

06/03/07 11:03 AM

#47947 RE: caravon #47915

Carovon, the paragraph you quoted, by itself, might suggest they were referring to a comparison of medians, but the first paragraph makes it clear the comparison is begtween hazard ratios:

"Patients receiving 15 mg/kg of Avastin plus gemcitabine and cisplatin chemotherapy experienced a 22 percent improvement in PFS (based on a hazard ratio of 0.82) (p-value = 0.0301) compared to patients receiving chemotherapy alone, and patients receiving 7.5 mg/kg of Avastin plus gemcitabine and cisplatin chemotherapy experienced a 33 percent improvement in PFS (based on a hazard ratio of 0.75) (p-value = 0.0026) compared to patients receiving chemotherapy alone."