Replies to post #46735 on Biotech Values

[gofishmarko]

>> Modigene (MODG) and is focused on drugs using the Carboxyl Terminal Peptide, whatever that is. <<


It's kind of a funny name for the technology , since all proteins already have a carboxyl terminal peptide , so it makes you wonder why they need another.

The amino- and carboxyl- ends of peptides and proteins are analogous to the 3' and 5' ends of a DNA strand , for example-- just a notation that reflects the binary structure of the individual components of the strands that is maintained throughout the strand , so that there is always a defined " front end " and "back end ".

MODG has just found a particular CTP that confers stability to proteins , so they'll produce CTP-modified proteins as an alternative to , say , PEGylated proteins.