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Replies to #593 on Biotech Values
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DewDiligence

12/10/03 12:18 PM

#594 RE: isolution #593

Thanks for the additional slides and clarifications.

I can’t recall if you have previously commented on REGN’s VEGF-Trap –i.e. whether it is likely to show better results than the kind of VEGF inhibition achieved by Avastin/Lucentis. If not, then perhaps now would be a good time to chime in :-)

I know that REGN’s partner, AVE, has plans to conduct human tests of VEGF-Trap in AMD. Moreover, VEGF-Trap has been given systemically in animal studies of AMD.



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DewDiligence

12/12/03 10:34 PM

#611 RE: isolution #593

Update on ophthalmic diagnostic acronyms:

>> Slide 18: FA and OCT immediately after first infusion, and just prior to next 3 infusions. <<

FA = fluorescein angiography

OCT = optical coherence tomography