Avastin use in lung cancer (both on-label and off-label) is growing in terms of the number of patients. However, $ sales are stagnant at best in the on-label setting because more and more oncs are treating patients with half the approved dose (7/5mg/kg instead of 15mg/kg) as a result of the data in the AVAIL trial (#msg-17277608, #msg-17353810).