<<<but i could envision a scenario where a side effect such as a rash could correlate to a heightened sensitivity to telaprevir or some other component of the triple therapy and hence serve as a biologic marker of response>>>
How would that work? The sensitivity is due to a protein in the patient's body interacting with the drug. Response for HCV is due to the virus' sensitivity to the drug. If anything, sensitivity of a patient to the drug may indicate that some of the drug is bound up by the patient and not as much is available for viral inactivation.
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