If you peruse the literature on Progeria it wont be long before you find an article speculating that the models for "goblins" seen in Renaissance paintings and in the reliefs on Notre Dame Cathedral were children with Progeria.
They say beauty is in the eye of the beholder Most people, including me feel children with Progeria have the facial appearence of the very old. The skin is thin, parchment like, non complient and has some similarities to Scleriderma.
Why don't we move on to fillers. I like your ideas about possible shorts. The filler business now is a little like the medical elctronic industry in the 70s. New products roll in to displace old ones. Overnight success and overnight failure.
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