Gfp: You are correct. I'm certainly not a neurochemist either, but allosteric actions like those of Ampakines are always reversible.
Half-life involves 1 and 2, both of which affect the length of time it takes for the plasma concentration of the drug to be reduced by 50%. #3 would not apply, it's the level of the drug, not the response of the system to the drug.
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