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DewDiligence

11/17/25 8:23 PM

#256465 RE: DewDiligence #256464

ENTA’s updated corporate slides (11/17/25)

https://ir.enanta.com/static-files/0b9a9564-339c-4501-8c98-eab636846bf4

There are a number of significant changes from the previous version of the slide set (from 9/29/25):

• Slide 3 updates the cash balance.

• Slide 4 (pipeline chart) replaces EPS-1421 with EDP-978, the new lead compound in the KIT program.

• Slide 6 (RSV population burden) is updated with recent data on outpatient visits, hospitalization, and deaths.

• Slides 29-31 have details about EDP-978 rather than EPS-1421.

• Slides 35-40 refer to EPS-3903 specifically (the newly selected lead STAT6 compound) rather than STAT6 prototype compounds generally, and there is updated (improved) data from preclinical models.