Replies to post #1865 on UniCycive Therapeutics Inc (UNCY)

[Whalatane]

Well there are some significant risks with Lupkynis .
eGFR ( kidney function ) typically declines in the first 3 mths then recovers in most ...but not all. Some patients have ended up with worse kidney function ...small number I think .
Theres also issues with elevated blood pressure and hyperkalemia in some and its only supposed to be prescribed to those with a eGFR over 45 .
As with many new drugs ...problems show up a year or two after approval ...once its used by the wider population .
Wife only knows of 2 patients on it and they monitor them fairly closely I think
Its very expensive with significant prior approval hurdles

Any bearing on UNCY ...well OLC is a reformulation of Fosrenol thats been used for years by thousands ...so less likely ( but not nonexistent ) .
Co may be required to have some kind of registry ...like ICU pediatric ...but doubt it would be more than that
JMO
Kiwi