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jondoeuk

09/18/25 7:49 PM

#811 RE: NY1972 #810

There is data showing that allo anti-CD19 CAR-T's lead to B-cell depletion in inflamed tissues.

From one: ''The immunohistochemistry further demonstrated that B cells were eliminated from the skin in both cases at the 3-month follow-up and remained negative in the skin at the 6-month follow-up even after the recovery of normal peripheral B cell level.'' https://www.cell.com/cell/fulltext/S0092-8674(24)00701-3