I believe some of these people can help themselves if they come out of their self installed bubble and insecurities by going outside and facing people in the real world. As simple as walking around a busy park or community area and observe people interacting with real people. Maybe a lot of these people imagine failure because they don't attempt to meet people out in the world but gauge their failure on internet interactions... which typically are the worst kind.
Sure it can be very complex, as complex as the human mind.