Vin- Thanks for the comments. Yes, the oral dosing is QD and the SC dosing is QW and the oral consumes far more API than the SubQ version. Actually I could easily tell you down to the milligram how much is being dosed in every arm down to the mg though each of the 13 week trial arms down to the mg fully accounting for the titration schemes but everyone here would probably be bored by that besides it being TMI.
So I will just give you a few key numbers. The SC dosing at 10mg QW over 13 weeks used 85 mg. The Oral 60mg QD arm uses 5040 mg of API and the 90mg "maintenance dose" uses 4830 mg. Importantly as a terminal run rate if you continue past 13 weeks you use 1800 mg at the 60mg dose and 900 mg at the 30 mg dose (the maintenance part of the 90mg arm). Both doses should yield considerable weight loss to begin with. Continuation of the 60mg might lead to considerable WL over a year and the 30mg maintenance dose should minimally maintain WL and possibly allow for continued WL over the long term.
Roughly over 3 months, you use about 5 grams (or 1.5g per month) of compound in the 2 ORAL doses I cited and then either 1 or 2 grams a month continuing. At say $400-500 month retail, both doses are commercially viable for Viking/Corden at "typical pharm margins" (again my personal "educated" guess)
I will have more to say on this soon but got to go now. Lately- the weather has been great in WNY and today is going to be spectacular on the lake.
Mufaso
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