I'm not in the least bit worried here. The pieces are coming together. My only concern will be in trying to get my sell orders re-entered. They expired today.
In October of 2020, Tucker interviewed Durrant about lenzilumab being a "Potential breakthrough coronavirus treatment." This was only about 7 months after covid hit our shores. This discovery of lenzilumab's potential to treat covid was the result of a Case Cohort Study led by Mayo Clinic, and included Humanigen's Dr. Cameron Durrant, Dr. Dale Chappell, and others, as trial investigators. A matter of 'all hands on deck.'
Results of the Case Cohort Study were published in June of 2020, and showed:
"Twelve patients were treated with lenzilumab. Clinical improvement was observed in 11 out of 12 (92%), with a median time to discharge of 5 days. There was a significant improvement in oxygenation: The proportion of patients with SpO2/FiO2 < 315 at the end of observation was 8% vs. compared to 67% at baseline (p=0.00015). A significant improvement in mean CRP and IL-6 values on day 3 following lenzilumab administration was also observed (137.3 mg/L vs 51.2 mg/L, p = 0.040; 26.8 pg/mL vs 16.1 pg/mL, p = 0.035; respectively). Cytokine analysis showed a reduction in inflammatory myeloid cells two days after lenzilumab treatment. There were no treatment-emergent adverse events attributable to lenzilumab, and no mortality in this cohort of patients with severe COVID-19 pneumonia."
Contemporaneous to Tucker's interview, Big Pharma began reporting the efficacy of their vaccines, in which most were claiming efficacy just slightly better than lenzilumab. Of course, THOSE claims were proven false. And vaccines were redefined from "preventing infection," to reducing hospitalizations and deaths.
Tucker's second interview of Durrant, in October of 2021 (a full year after Tucker's interview to discuss how lenzilumab's efficacy was demonstrated), was intended to expose how "Treatments for Covid Are Being Ignored By FDA."
You've been here since 2015, just as I have. It's despicable that you would now claim that these results have been a scam. I have made it clear as day that the NIAID/NIH ACTIV-5 government-sponsored trial was designed to fail, by including late-stage patients in Ordinal Scales 5, 6, and 7, and excluding patients in Ordinal Scale 4, who accounted for 78% of the LIVE-AIR trial population. Humanigen included early-stage patients only in Ordinal Scales 4 and 5.
ACTIV-5 patient inclusion criteria:
Illness of any duration, and requiring, just prior to randomization, supplemental oxygen (any flow), mechanical ventilation or Extracorporeal Membrane Oxygenation (ECMO) (ordinal score 5, 6, or 7).
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