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Mufaso

05/17/23 4:58 PM

#247034 RE: DewDiligence #247032

Thank you- you are correct. I had trouble formatting the post using Ihub tools. Maybe the improvements coming will make tables like this easier to format/read. I redid the table of failed NASH drugs with trialcompleted and your corrections on MOA below:

Selonsertib (Gilead) ASK1 inhibitor Multiple Ph 3
Simtuzumab (Gilead) Anti-Loxl2 MAb Ph 2
Px-102 (Gilead) FXR agonist Ph 2
Elafibranor (Genfit) PPARa/d agonist Ph 3
Emricasan (Conatus) pan-caspase inh Ph 2b
Ocaliva (Intercept ) FXR agonist Mult Ph 3
Seladelpar (Cymabay ) PPAR-delta agonist Ph 2b
Semaglutide (NOVO) GLP-1 ag Ph 2
PF-06882961 (Pfizer) GLP-1 ag Ph 1
PF 06835919 (Pfizer) Ketohexokinase inh Ph 2
NGM-219 (NGM ) UPR inducer Ph 2b
BI 1467335(Boehringer) Pan-caspase inh ph 2