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Replies to #5125 on Entremed (ENMD)
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rkopenec

02/19/07 5:39 PM

#5126 RE: vk707 #5125

Sure makes you wonder about the combination study of Panzem NCD with Avastin in metastatic carcinoid tumors. Didn't Burns convienently skip it in his last presentation?

From what I understand, the trial is currently still enrolling.

If they started enrolling immediately (May 2006), we could have some interim trial results.

I'd love to see CELG and DNA get in to a bidding war for Entremed..... Some pretty deep pockets.

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docaaron1

02/21/07 10:03 AM

#5128 RE: vk707 #5125

IMO, anything that Avastin can do, Avastin and Panzem can do better. Anyone know if there was any mention of posterior leukoencephalopathy syndrome in the Avastin-Glioma study?

I would still suggest giving Panzem before Avastin but like the Panzem/Velcade study showed the HIF-1a inhibition results may be only slightly improved but still improved.

Aaron