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dewophile

04/11/23 2:30 PM

#246360 RE: DewDiligence #246347

yes this could get to be a crowded space
here is some phase 2 data from BAVA FWIW

https://www.medrxiv.org/content/10.1101/2022.12.02.22283030v1.full-text

vaccine efficacy ranged from a low of 9.6% for infection confirmed by laboratory measure only to 58.7% for infection confirmed both by laboratory measure and by the presence of at least one RSV symptom of grade ≥2, and the differences in infection incidence between the treatment groups were not statistically significant. When infection was defined instead by quantifiable qRT-PCR viral load, efficacy ranged from 51.8% to 79.3%, and differences in symptomatic infection were statistically significant. Finally, when defined by virus culture results alone, vaccine efficacy was 88.5% (p=0.0125); addition of clinical symptoms to the definition did not improve efficacy.



There was a larger phase 2 w 400+ patients but I couldn't find any data. however the results of this call it phase 2b trial did get them BTD and Prime, so I am assuming the data was relatively strong