First line will be different and more derisked than R/R. R/R : goal is an approval of 818 as MONOTHERAPY by achieve orr 25-30% and mDor > 6 MO 1s line : goal will be approval of 818 as a COMBINATION with CHOEP. Regarding the different kind of moa between these two treatments, we could anticipate in derisked manner and with confidence that if 818 will be approved in R/R as monotherapy, drug will be approved in 1st line to. This is why I think it is a 2023 story.
First line will be different and more derisked than R/R. R/R : goal is an approval of 818 as MONOTHERAPY by achieve orr 25-30% and mDor > 6 MO 1s line : goal will be approval of 818 as a COMBINATION with CHOEP. Regarding the different kind of moa between these two treatments, we could anticipate in derisked manner and with confidence that if 818 will be approved in R/R as monotherapy, drug will be approved in 1st line to. This is why I think it is a 2023 story.