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dewophile

11/04/22 11:04 AM

#244417 RE: DewDiligence #244414

Thanks I missed that in the slide deck and if there was a presentation didn't bother listening. Roger about the core inhibitor too
It seems everyone is using Galnac for liver targeting (both siRNA and ASOs) except for GSK (roche JNJ etc), and counterintuitively at least for GSK naked ASO much better than liver-targeted ASO (GSK has a theory on this that I posted previously)

so far naked ASO>> siRNA > or = GalNac ASO,. naked siRNA??