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dewophile

10/20/22 5:30 PM

#244235 RE: DewDiligence #244234

yes
serious AEs are no different, just things like injection site pain and mild self limiting systemic stuff
so that is why I would want the efficacy boost w GSK (which is there despite all the talk about difficult cross trial comparisons)
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dewophile

10/20/22 7:51 PM

#244240 RE: DewDiligence #244234

I just looked it up and shingrix is associated with an excess of 3 cases of GBS per million doses. I wasn’t aware of this. Even though they use a half dose adjuvant for RSV this will be some thing to monitor if approved and given on wide scale (I guess for PFE too since they reported 2 cases in trials now too)