The color brown or black on a cat is carried on the x chromosome.
In order for a cat to be calico or tortoise shell colored it needs to have two x chromosomes, hence a female cat. So how does the occasional male pop up with that coloration? It's a cat with an xxy combination of chromosomes. It is by definition a non-binary animal... a two spirit cat if you will... that occurs naturally.
Do we understand how that fits into the conversation?
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