Do you know what causes the improvement in sight in response to squalamine? Is it because the "new" blood vessels have just shrunk?
Much of the loss in sight, especially a severe loss, in AMD occurs when the blood vessels start leaking blood under the retina. I admit, I do not know what the mechanism is for removing the blood in this circumstance.
As I recall, it is macrophages in your blood and lymph system that clean up "bruises" in your body that result from broken blood vessels when you fall or whatever. I don't know if they work in the eye or not.
Just some random thoughts.
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