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DewDiligence

06/29/22 10:55 AM

#243022 RE: DewDiligence #241789

ICVX -26% on purportedly-positive phase-1b data_for RSV vaccine:

https://finance.yahoo.com/news/icosavax-announces-positive-topline-interim-200500639.html

The stock is down 58% from its IPO less than a year ago (#msg-165173004).
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DewDiligence

07/29/22 2:38 PM

#243340 RE: DewDiligence #241789

ICVX says it knows why its COVID vaccine failed, but will anyone care?

https://finance.yahoo.com/news/icosavax-announces-results-ivx-411-200500918.html

Icosavax…today announced the results from an end-to-end drug product investigation of IVX-411, a VLP vaccine candidate displaying the SARS-CoV-2 receptor-binding domain (RBD). This investigation was initiated following the company’s Phase 1/2 topline interim data results in which the immunologic response observed for IVX-411 was inconsistent with expectations based on known data for the company’s platform and VLP technology.

…The RBD antigen component (Component A) of IVX-411 becomes unstable during manufacturing and subsequent storage at 2-8 °C…