Merck Research Laboratories president Roger Perlmutter said: “Scientists at Immune Design have established a unique portfolio of approaches to cancer immunisation and adjuvant systems designed to enhance the ability of a vaccine to protect against infection, which could meaningfully improve vaccine development.
The drug candidate has been evaluated in various clinical trials, including in combination with Merck’s anti-PD-1 checkpoint inhibitor Keytruda.
“This acquisition builds upon Merck’s industry-leading programmes that harness the power of the immune system to prevent and treat disease.” The company’s lead product candidate G100 is a potent intratumoral TLR4 agonist designed to use a range of endogenous antigens to generate a systemic anti-tumour immune response. It is indicated for Non-Hodgkin’s Lymphoma.
Gluck, Immunopotentiating Reconstituted Influenza Virosomes (IRIVs) and other adjuvants for improved presentation of small antigens, Vaccine, 10(13):915-9 (1992).
Market Data 
Markets 
AI
