Replies to post #145857 on NanoViricides Inc (NNVC)

[KMBJN]

Nanoviricides: sound concept, horrible execution.

Here once again, non-related scientists take the concept of nanomolecules (in this case natural exosomes) with viral ligand on them (in this case, ACE2, same as NV-CoV-2) and use them to treat viral disease in animal models.

Exosomes are definitely safe (all cells produce them naturally).

https://phys.org/news/2022-01-nano-sized-vesicles-ace2-receptor-infection.html

These natural ACE2 exosomes, like NV-CoV-2, are broad-spectrum, i.e. effective against multiple CoV strains in mice:

https://www.nature.com/articles/s41467-021-27893-2

Our observations demonstrate that evACE2 is a decoy antiviral mechanism to prevent SARS-CoV-2 infection, thus providing a rationale for the use of evACE2 to combat COVID-19.

Will NNVC ever put one of their nanoviricides into humans?