“The RFN vaccine candidate is more compact and has some natural advantages as we try to increase the immune response against multiple coronaviruses using a single vaccine platform, so it is still under consideration as part of our pan-coronavirus vaccine development pipeline,” said WRAIR structural biologist and vaccine co-inventor, Dr. Gordon Joyce.
High titer neutralizing antibodies have been reported with a balanced Th1/Th2 response when mice were immunized with reconstituted virosomes produced from RSV envelopes containing a lipopeptide adjuvant [48]
Stegmann T, Kamphuis T, Meijerhof T, Goud E, de Haan A, Wilschut J.
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