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Replies to #41388 on Biotech Values
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daved

01/31/07 7:23 PM

#41398 RE: fid #41388

Re MCU. What possible relevance does the absolute number of incidences have to do with the discussion?

The numbers have to be large to reach the significance numbers reported.

What is your source for the P2 mortality statement? I've not noticed it in the literature.

Dave

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iwfal

01/31/07 11:24 PM

#41409 RE: fid #41388

From the Phase II 900 patient trial can you please explain how many patients would have had a peak CK-MB greater than or equal to 100ng/ml to put it in proper perspective and show why the failure of the primary endpt of 50ng/ml is significant?

The answer is about 50 in the placebo arm assuming it is 300 patients per arm.

FWIW. (and it was somewhere near 15 +/- 3 that had "physician diagnosed MI" in the placebo arm)