Replies to post #409562 on NorthWest Biotherapeutics Inc (NWBO)

[beartrap12]

Great post, bright Boy.
Senti, Dr. Bala, This post explaining why we’re still so far ahead of the competition, should be stickied!

[exwannabe]

... , I would suggest that people reread the latest patent granted Northwest. The breadth and width of that patent is very expansive and makes it very difficult for our competition to advantage their companies to our technologies.

You got to be kidding me.

The patent is specifically for a "method B DCVax-Direct" that is matured for about 16 hours (they disallowed 12-20) using a sauce that includes the BCG vaccine. It has nothing at to do with with DCVax-L.

Nobody knows if protecting Direct is worth anything. They ran a P1 trial 6 years ago. Since then nothing. The only trial on the books is another P1. And nobody knows if this would even be the best way to make a "Direct". That would be the secret sauce.

[biosectinvestor]

Nicely said Bright Boy. Yes, individualized, customized treatment is the advantage here and I think it will prove to be the core of a gold standard that may include other treatments to address the idiosyncratic pathologies of different cancer types and patient responses, but it will be, assuming things turn out as many of us expect, the way to craft an immune response exactly customized to all the antigens in that patient’s tumors. And let’s not forget that there will be two approaches including DCVax-L and DCVax Direct, and those will afford even more powerful ways to customize the immune response for that patient’s exact cancer. The mRNA approach is nothing like that, and takes the ideas back to static approaches that are intended to hit big and/or broad targets. They can add targets easily, after trials, once they learn perhaps that they did not get them all, but that is the same hit or miss approach that has been haunting cancer vaccines for a long time.

[reachjo]

Drop mic BB!

[Sir Pumpernickel]

That ALL sounds great so if you can say it why can’t the company? No disrespect intended but I really don’t GAF what a poster on a message board says! It’s time foe the share holders to hear from the COMPANY!!! NOT YOU!! Again no disrespect but I don’t know you from Adam!!!!!
Pumpernickel YuYU.. YuYU...YuYUYuYu YuuuuuuuuLaAAAAAAAAAAWWWWWWWWWWWHHHHHHHHHHHOOOOOOOOOOoooooooooEeeeeeeeeeeeeeeee!!!!!!!!!!!!!!!!!

[CrashOverride]

Well said. There's also no need to use mRNA (messenger RNA) because it's an unnecessary middle man. We do not need mRNA to communicate the antigens present on the tumor, which would be gotten through sequencing the tumor, to the dendritic cells. We present the dendritic cells directly to the tumor. DCVax will always be more accurate and efficient than mRNA cancer vaccines.