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loanranger

08/01/21 8:55 PM

#368283 RE: petemantx #368282

"We know it is safe from the raising of dosing from 3 days to 5 after 30% of patients had gone thru active phase of trial"

Close, no cigar.

"Upon reaching 25 percent enrollment (30 subjects)"
http://www.ipharminc.com/press-release/2021/4/5/innovation-pharma-completes-interim-safety-data-reviewdmc-approves-increased-dosing-frequency-in-phase-2-clinical-trial-of-brilacidin-in-hospitalized-covid-19-patients
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sunspotter

08/02/21 8:37 AM

#368339 RE: petemantx #368282

“Brilacidin actually KILLS the virus so viral load HAS to drop dramatically, and the SOC is currently near 0 (a total waste) so how could efficacy not be pronounced? “

Very easily. Just one of the ways it could fail is if its in vitro MoA is due to phospholipidosis (which has nothing to do with claims that that is ann vivo side effect as others have misunderstood).

Consider also that remdesivir is more effective than brilacidin in vitro but only marginally effective in vivo.