When used to treat diabetes, the tech’s pinhead-sized, porous capsules are filled with insulin-producing cells
Except it will never happen. There are currently no licensed insulin producing cells to put into the cellulose beads. The UTS cell line is kaput.
The announcement noted that this is exactly what the enzyme system in a person’s natural liver would normally do.
Prove it. Provide a link which measured how much of a given dose of Ifosfamide is converted by the magic CIABs. As opposed to the liver.
It gets active ifosfamide to the cancerous cells more quickly, which is crucial as the drug has a short half-life.
Prove it. Provide a link that shows Ifosfamide can easily penetrate the stromal layer of a pancreatic tumor. One should also lookup the meaning of "half life".
When treating pancreatic cancer, the approximately 30,000 live cells that the capsules are filled with convert inactive chemotherapy drugs (ifosfamide) into an active, cancer-killing treatment.
No it won't. Ifosfamide was shown to be ineffective against pancreatic cancer by others.
Ifosfamide has no effect until it is activated in the liver; therefore, this system could prove particularly useful in limiting the effect of chemotherapy on the body, as it travels through uninfected areas.
That statement doesn't even make sense. Ifosfamide as it "travels through uninfected areas" would have a systemic effect.
PharmaCyte claims that “because of the smaller dose, the treatment can be administered without any side effects from the chemotherapy.”
An unsubstantiated, and false claim by PMCB.
The tech has been tested and found effective in past clinical trials.
Another false statement on the part of PMCB. There has never been any clinical trials sanctioned by the FDA conducted.
The Cell-in-a-Box will be used in the way described above for an upcoming Phase IIb clinical trial.
No it won't. The IND for a Phase 2b will never be approved by the FDA. There's nothing to support skipping Phase 1-2a.
So how many years away is that awesome technology.
Cell-in-a-Box, can act both as an artificial pancreas and an artificial liver. Thus, the tech can be used in the treatment of Type 1 and Type 2 diabetes as well as advanced pancreatic cancer.
When used to treat diabetes, the tech’s pinhead-sized, porous capsules are filled with insulin-producing cells, the company said. In the case of advanced pancreatic cancer treatment, those same capsules are filled with genetically modified cells that behave as a sort of artificial liver.
Until into actual testing this is NOTHING BUT CONJECTURE~! Nothing but bullshit to stir the masses......
So where is the IPC CiaB IND? On hold...... still? The FDA Kenny do list still being addressed? Waiting for Futon Motors to make a comeback with a CiaB battery powered car.