Stock Jodi , actually , I will agree with this request to some point in very early infection only ,
Just not alone with Bamlanivimab , since lately study in monotherapy showed no effect..
All these neutralizing monoclonal antibodies working at the very beginning of covid on spike protein of the virus ..
I remember with REGN-cov2 about 50% of virus could be neutralized , and then our body should be strong enough to get rid of rest , or patients will go to the immunological stage and it will need other drugs as Leronlimab...
REGN-cov2 has 2 different neutralizing antibodies , each working on different area of spike protein , so is little less sensitive to mutations.
Lets look at President Trump treatment .
In AM they gave him REGN-covid2 , he was getting worse so in the evening they started 5 days therapy with Remdesivir.
Still 2 days later his lung scan show beginning of inflammation , blood oxygen went down < 93 % , and doctors added dexamethasone..
I believe that if they give him REGN-cov2 plus Leronlimab he will not need anything else..
Actually I believe that only Leronlimab will do the job , but I will not completely object to REGN-cov2 given with Leronlimab at the beginning of this disease , as I am objecting to using with Remdesivir..
Lets remember , neutralizing monoclonal antibodies decrease VL ( if ) , when given early , but they do nothing else , they do not work on our immunological system ,
and they may have some side effects , including severe allergic reaction.
This is why infusion is done for about one hour , and then 2-3 hrs observation...
This is All IMO.
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