Replies to post #236798 on Biotech Values

[DewDiligence]

ENTA—I'm inferring that the HBV RNA destabilizer could aid the antiviral; thus increasing the net viral load decline. The destabilizer alone may create it's own viral load decline, but my sense is that like ribavirin, it weakens/disrupts the virus and will work synergistically with the antiviral.

You could be right. Ribavirin was an obligate component of early HCV regimens despite its being a weak nucleoside that generated only a ~1-log reduction in viral load on its own.