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mick

01/02/21 6:04 PM

#228099 RE: mick #228098

Pfizer/BioNTech one, nor for Moderna's. No studies have been designed to find that out, so all we can do is guess based on what we've seen with the interval between doses in the two-dose studies. That's been encouraging with the two mRNA vaccines, but remember: we don't know how they are over a longer period, because no one was left without a second dose for that long. It's certainly possible that without the second booster, the protection seen after one shot starts to wane. We do not know. And we know even less about the Oxford/AstraZeneca vaccine's behavior under these conditions. Giving as many people in the UK as possible a single dose of that vaccine with a longer wait until the booster is a gamble, and you wouldn't want to do it that way if the alternatives weren't even worse. It's the right move, unfortunately, and it's a damned shame it's come to this. Update: the UK is now planning to try this with the Pfizer/BioNTech vaccine as well - thoughts here.