Replies to post #339762 on Elite Pharmaceuticals Inc (ELTP)

[WeeZuhl]

The idea that there is risk in manufacturing opioids is not ludicrous nor incomprehensible. What other explanation can you come up with for Elite not being able to 'give' away their approved acetaminophen and Codine?

Nobody wants Tylenol #3 because nobody wants codeine. It is a weak analgesic with a limited therapeutic window. It requires higher doses for effective analgesia, but it has the typical opioid side effects (i.e. nausea, lethargy) at those doses. In 2017, FDA restricted codeine use in kids (which was a full 18 months before Elite filed the ANDA). Oxycodone, hydrocodone, and hydromorphone are much stronger, and therefore they are much more effective at lower doses, which means the side effects are much less. Methadone tends to have more side effects, but it has the benefit of a longer half-life and is longer lasting.

It was a waste of money to develop, and that is why nobody wants to waste their money to buy it. Please don't confuse Nasrat's stupid decision to develop codeine with some rational explanation for the Great Opioid Massacre of 2019. And also, don't mistake Nasrat's smart-alecky disdain for Elite shareholders as one of his positive attributes.

As for whether or not opioids are over-prescribed, yes, for sure, but not as much lately as in the past. For chronic pain, I tend to have better luck over the long term with some old non-narcotic favorites, like escitalopram and bupropion, and new friends, like pregabalin. But there is a role for opioids for acute and breakthrough pain, and I refuse to leave my patients to suffer when there is something I can do about it. I've said it before on this board, in regards to lumbar spinal stenosis, I've made people walk again with a fentanyl patch. Very low side effective profile, very effective drug. Should I leave those people in pain in their wheelchairs because I have a moral objection to fentanyl? Not me.

[Just give me $1.50]

LMAO!!!!!

Nasrat is not looking to sell that drug. Never has. Never will.

That's why there has never been any buyers. Was never for sale!

Read the 10-K.

Acetaminophen and Codeine Phosphate

The Company received approval from the FDA of an ANDA for a generic version of Tylenol® with Codeine (acetaminophen and codeine phosphate) 300mg/7.5mg,300mg/15mg, 300mg/30mg and 300mg/60mg tablets. Acetaminophen with codeine is a combination medication indicated for the management of mild to moderate pain, where treatment with an opioid is appropriate and for which alternative treatments are inadequate. Acetaminophen with codeine products have annual U.S. sales of approximately $45 million according to IQVIA (formerly QuintilesIMS Health Data). The Company is not pursuing licensing deals for any opioids at this time until the market changes. The Company will wait for the market to stabilize before pursuing these opportunities.

On a recent call Nasrat said he has been trying to sell Elite's right to acetaminophen and Codine. If your right about there being zero worry for a drug company to sell opioids why aren't three any takers for this drug? He even sarcastically asked stock holders on the phone to have interested parties give him a call. It should be well known amongst potential buyers that Nasrat will give them an amazing deal to get it off his hands.